JTPM
Journal of Translational and Practical Medicine

Journal of Translational and Practical Medicine regularly publishes internationally qualified issues in the field of Medicine in the light of up-to-date information.

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Original Article
Treatment outcomes of our patients with prostate cancer who underwent postoperative radiotherapy
Abstract
Aims: Prostate cancer is one of the most common cancers in men. Surgery, radiotherapy or active surveillance are the treatment options. Treatment is decided according to risk group of the patient. Postoperative radiotherapy is delivered in selected patients to increase the local control rates. The aim of this study is to report the treatment results of patients who received postoperative radiotherapy for localized prostate cancer.
Methods: This retrosepctive study included 78 prostate cancer patients who received postoperative radiotherapy between 2011 and 2023. All patients except who had pathologically positive lymph nodes were included into the study. Overall survival, progression free survival, and associated pathological parameters were evaluated by using IBM SPSS programme version 20.
Results: The mean follow-up time was 66.7 (IQR 25-75:41,6-89,6) months. Five and 10-year overall survival rates were 93%, and 67.3% respectively; (median (95% CI); NR (not reach): while 5 and 10-year progression-free survival rates were 90.3%, and 50.4, respectively; (median (95% CI); 135.3± (105.9-165.7). Postoperative prostate specific antigen (PSA) and pre-RT PSA values, and the effects of these parameters on progression-free survival was analyzed, median progression-free survival was higher in patients with postoperative PSA values ? 0.185 (135.6±24.4 vs 113.3±6.4, p:0.001). Five and 10 year overall survival and progression-free survival rates of patients with a high gleason score who underwent postoperative radiotherapy was observed lower than the others (86.9% and 46.3%, p=0.006; 86.9% and 33.8%, p=0.009 respectively).
Conclusion: Postoperative radiotherapy is generated best results in progression free survival and overall survival in patients with low pre-rt psa and high gleason score prostate cancer cases

Keywords : Prostate cancer, radiotherapy, postoperative radiotherapy

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Article available in :
Volume 2, Issue 2, 2023
Page : 41-45
https://doi.org/10.51271/JTPM-0039
Article Information
Received : 14 Tem 2023
Accepted : 28 Ağu 2023
Published : 31 Ağu 2023
Corresponding Author :

Esra Kekilli: Department of Radiation Oncology, Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital, Ankara, Turkey

[email protected]
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